Ventsislav Dobrev
Global Clinical Integration Lead Digital Biomarkers Roche
Ventsislav Dobrev is a seasoned healthcare and life sciences professional with over two decades of experience across pharma, medtech and healthtech. He has held leadership positions at large organizations including IQVIA, Novartis, Ypsomed and Roche. Currently, he leads a global function at Roche which is responsible to integrate digital biomarkers in clinical trials.
Seminars
Wednesday 2nd December 2026
Accelerating CNS Clinical Trials & Detecting Earlier Efficacy Signals Through More Sensitive Digital Biomarkers
2:00 pm
- Explore how digital biomarkers are being established alongside standard clinical scales to measure disease progression and drug effect in Parkinson’s, Huntington’s disease, and other rare neurological conditions including their implementation as primary endpoints in Phase II and secondary endpoints in Phase III programmes
- Discover how sensitive, longitudinal digital biomarker measures can enable Phase II studies to run two to three times faster with two to three times smaller sample sizes, reducing clinical trial costs while detecting earlier signals of drug efficacy
- Examine how virtual control arms generated from natural history study data can identify early efficacy signals in Phase I studies
